Important discovery of Polish scientists on avian influenza – Polish Radio

  Tests the commercial implementation can be useful in diagnostic laboratories controlling poultry farms , photo: Glow Images / East News
 

The two types of biosensors have been developed: using infected with the body’s ability to produce antibodies immunoczujniki and genoczujniki, whose task is to capture the signals of environmental contamination, identifying them and logging.
As explained by prof. Hanna Radecka from the Institute of Animal Reproduction and Food Research of the Polish Academy of Sciences in Olsztyn, the first type of immunoczujników on the electrode which forms part of the measuring system are placed specific antibodies that have the ability to detect in biological material, pathogens of the presence of avian influenza virus.
In the second type of immunoczujnika – as explained by Professor. Radecka – the situation is reversed, on the electrode is placed inactive portion of the pathogen (virus fragment), and with his help can be detected in biological material specific to the antibody.
Immunoczujniki – convince Polish scientists – are more sensitive, cheaper and require less volume of sample to be analyzed than the ELISA method widely used for the detection of avian influenza virus. – Immunoczujniki have used for analysis of real samples. We distinguished successfully obtained sera from vaccinated and unvaccinated chickens – stressed the expert from the Institute.
second type of sensors developed by the researchers, this genoczujniki Olsztyn based on specific DNA sequences of avian influenza virus. Construction genoczujników refers to an electrode placed on a predetermined sequence of the genetic code, whose task is to detect the target sequence in the pathogen DNA present in the biological material. According to the authors, genoczujniki have alertness similar to that used traditional PCR and at the same time are less expensive.
– This is not yet the finished product to be used immediately in specialist laboratories. We have shown that the developed sensors can be successfully applied to the analysis of real samples and effectively detect both parts of the H5N1 virus and antibodies which – pointed prof. Radecka. – Presently looking for partners to commercialize sensors developed and introduced to the market. The sensors have a high potential for application. They can be miniaturized and so widely used – she added.
Sensors develops a team led by prof. Hanna Radecki, in collaboration with the Institute of Biochemistry and Biophysics, Polish Academy of Sciences in the framework of the project “Centre for biotechnology medicinal products. A package of innovative biopharmaceuticals for the treatment and prevention of human and animal.” Biological material which is subjected to tests for the detection of avian influenza in poultry are their saliva and feces.
PAP, kk