Tests for avian influenza in poultry based on the presence of antibodies specific to the virus or using a specific sequence of DNA code developed scientists from Olsztyn.
Testing the commercial implementation can be useful in diagnostic laboratories control of poultry farms.
sensors designed to detect the H5N1 virus develops a team led by prof. Hanna Radecki of the Institute of Animal Reproduction and Food Research of the Polish Academy of Sciences in Olsztyn, in collaboration with the Institute of Biochemistry and Biophysics, Polish Academy of Sciences in the framework of the project “Centre for biotechnology medicinal products. A package of innovative biopharmaceuticals for the treatment and prevention of human and animal.”
Scientists have developed two types of biosensors: immunoczujniki and genoczujniki, whose task is to capture the signals of environmental contamination, identification and recording them.
Immunoczujniki use infected with the body’s ability to produce antibodies.
Professor explained. Radecka, the first type immunoczujników electrode which forms part of the measuring system are placed specific antibodies which have the ability to detect biological material of the presence of pathogens avian influenza virus. In the second type of immunoczujnika situation is reversed, on the electrode is placed offline portion of the pathogen (virus fragment), and with his help can be detected in biological material-specific antibodies for him.
As the authors argue immunoczujniki developed are more sensitive , cheaper and require less volume of sample to be analyzed than the ELISA method widely used for the detection of avian influenza virus.
– We used to analyze real immunoczujniki trials. We distinguished successfully obtained sera from vaccinated and unvaccinated chickens – emphasized prof. Radecka.
The second type of sensors developed by the researchers, this genoczujniki Olsztyn based on specific DNA sequences of avian influenza virus. Construction genoczujników refers to an electrode placed on a predetermined sequence of the genetic code, whose task is to detect the target sequence in the pathogen DNA present in the biological material.
According to the authors, attention genoczujniki have used similar to conventional PCR methods and are also its cheaper.
0- This is not yet the finished product to be used immediately in specialist laboratories. We have shown that the developed sensors can be successfully applied to the analysis of real samples and effectively detect both parts of the H5N1 virus and antibodies which – emphasized prof. Radecka
– is currently looking for partners to commercialize sensors developed and introduced to the market. The sensors have a high potential for application. They can be miniaturized and so widely used – said prof. Radecka.
biological material, which is subjected to tests for the detection of avian influenza in poultry are their saliva and feces.
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