Life-prolonging drugs are already available – Virtual Poland

Scientists seek “youth pill”, while life-prolonging drugs are already available. Many people have used them every day without being aware of it – says American gerontolog prof. Brian K. Kennedy in “New Scientist”.
 

So far, there seemed to be approved for use only medications are helpful in the treatment of diseases. If you were told that prolong life, it is only because we treat disease. Examples are medicines that reduce blood pressure, protect against heart attack and stroke.
 

Head of the Buck Institute for Research on Aging in Novato, California, prof. Brian K. Kennedy argues that some pharmaceuticals can directly affect the aging process. This behavior is a side effect of these drugs, in this case a very positive.
 

 - Some experts have already started taking them only just to prolong his life – said prof. Kennedy during the international symposium on the subject, which was held in September 2014, the. In Basel. An additional advantage of some of these drugs is that they are cheap.
 

One such preparation is metformin has long been used in the treatment of diabetes type 2. First of all, it helps diabetics, reduces glucose levels and reduce the risk of complications of diabetes and premature death. It has been shown, however, that in healthy rodents by 5 percent. prolongs life. – Works like a low-calorie diet slows the aging process – said Dr. Rafael de Cabo of the National Institute on Aging in Bal timore in “Nature Communications”.
 

Do the same with men? Lack of such studies have not yet carried out. British experts compared the diabetics taking metformin but with people of a similar age who do not have diabetes type 2.
 

As expected patients taking metformin patients lived longer than other diabetics taking other antidiabetic drugs. However, the average length of life was also about 15 percent. longer compared to people without diabetes who do not use this drug.
 

Prof. Kennedy says that life can also prolong cardiac medications such as statins and aspirin. Statins lower cholesterol in the blood, which inhibits the development of coronary heart disease and reduces the risk of heart attack and stroke. On the other hand, aspirin, and aspirin properly, which is the main component, acts antithrombotic and anti-inflammatory.
 

Statins also have anti-inflammatory and reduce the risk of gallstones. Maybe protect against cancer. “New England Journal of Medicine” published in June 2014. Danish research experts suggest that people taking these medications by 15 percent. less likely to die of cancer.
 

The antitumor effect of acetylsalicylic acid exhibits. In numerous tests, it was found that it reduces the risk of colon cancer. In this year, “Cancer Epidemiology, Biomarkers & amp; Prevention” wrote that the regular intake of this drug also reduces the risk of pancreatic cancer.
 

The preventive use of statins and aspirin is still disputed. At the moment there is no conclusive evidence that taken in small doses to protect people from heart attack or stroke. Both drugs are prescribed by doctors only in the secondary prevention of heart attacks and strokes.
 

A more promising research on rapamycin, a drug used in human transplantation, it helps prevent transplant rejection. Animal studies have shown that it also acts as a “pill of youth”: allows you to keep in good physical condition, reducing the risk of cancer and cardiovascular disease, even improves cognitive function.
 

In any case, the mice fed rapamycin lived significantly longer than other rodents.
 

– Rapamycin may be not only a way to extend life, but also the prevention of diseases associated with aging and improve health – says one of the authors of this study, Viviana Perez from Oregon State University (USA) in “Journals of Gerontology: Biological Sciences.”
 

Some researchers are already thinking about a nutshell complex containing metformin and rapamycin that protects against disease and prolonged life. For now, tests are conducted on a medicine that contains a statin, aspirin and blood pressure lowering agent.
 

Life can even extend the use of certain antiviral drugs. Convinces the Dr Paul Moss of the University of Birmingham. Scientist for 18 years he observations of 500 people over 65 years of age. He said that 70 per cent. they were infected with cytomegalovirus (CMV).
 

– We have established that people with CMV live an average of four years shorter – said a specialist in “New Scientist”. For comparison, shortens life like smoking and alcohol abuse.
 

cytomegaloviruses is widely prevalent in the world herpesviruses. They are generally harmless, cause only a mild sore throat and fever, without causing complications. Most people are not even aware of the infection, but the germ often remains dormant in the body for life.
 

Dr Moss announced that it intends shortly to confirm his findings in human clinical trials over 65 years of age.
 
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